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Conditioning?

Lisa A Romano v055pcqa at ubvms.cc.buffalo.edu
Mon Nov 8 14:43:00 EST 1993


In article <BILL.93Nov5130224 at dentate.nsma.arizona.edu>, bill at nsma.arizona.edu (Bill Skaggs) writes...
>markb at orl.mmc.com (Mark Bower) writes:
> 
>   William White asked>i> 
>4) If there is no intracellular magnesium, then glutamate alone is
>sufficient to cause current flow -- postsynaptic depolarization is no
>longer necessary.  (Ordinarily, glutamate opens the channel but it
>gets clogged by magnesium ions unless there is enough postsynaptic
>depolarization to pull the magnesium away from the channel opening.)

> I thought extracellular Mg++ blocks the channel!!! 
>If you speak C,
> 
>  Current = Glutamate && (Depolarization || !Magnesium) && Glycine;
> 
>	-- Bill



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