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Habituation and Conditioning

Kermit Rose rose at garnet.acns.fsu.edu
Sun Nov 21 22:15:38 EST 1993

erwin at trwacs.fp.trw.com (Harry Erwin) writes:
> When an afferent stimulus is repeated, but not attended to, the synapses
> involved habituate. This occurs on the presynaptic side and appears to
> involve depletion of Ca++ in the extracellular fluid at the synapse. (Ca++
> is required for vesicles to attach and release their contents.) On the
> other hand, if the stimulus is attended to, so that the post-synaptic side
> is depolarized to some degree, conditioning occurs. Is the Ca++
> concentration maintained in the synapse during conditioning? Or is the
> depletion more than counterbalanced by the conditioning process? This is a
> significant issue if one is trying to simulate learning processes in mass
> action models.
> Cheers,
> -- 
> Harry Erwin
> Internet: erwin at trwacs.fp.trw.com
>           herwin at cs.gmu.edu
> Working on Freeman nets....

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