An absence of uptake mechanisms is probably too strong a contention. The
action is primarily at extrajunctional receptors, and so I would expect
that the density of uptake enzymes would be less than at a synaptic
density, however, I should have thought that they were still bound to
be present. I agree however that these actions, and that of the extent
of neurotransmitter drift, are important issues for investigation.
Richard M Vickery \ /
ucgbrmv at ucl.ac.uk (oVo) Our Quest is for meaning,
ph. 44-71-387 7050 x3256 ) ( but the Meaning IS the quest.
fax 44-71-383 7005 ^ ^