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[Microbiology] Methyl-Citrate-Cycle - Context and Questions

Keno März Dr.K.No at gmx.de
Sat Mar 4 10:41:13 EST 2006


Hello everyone!

I'm a student from Germany, and going through my Microbiology lessons, I 
stumbled over the Methyl-Citrate-Cycle (I hope this is the correct 
translation). It is connected with the dissembly of Alkanes (German: 
Beta-Oxidation). This is what I believe to know:
- In case the Alkane contains an uneven amount of C-Atoms, the Product 
of the Beta Oxidation is Propionyl-CoA, which is then processed to 
Methyl-Isocitrate by the Methyl-Citrate-Cycle.

My Questions:
- Is the above correct? (That's a stupid one)
- What happens to the Methyl-Isocitrate?
- During the course of the Betaoxidation of a C15-Fatty-Acid, would the 
Products be several Acetyl-CoA and exactly 1 Propionyl-Coa, or several 
Propionyl-CoA?


I hope I made myself clear, it's not easy for me to translate from 
German in this highly specific subject. I'd really appreciate any help 
and clarifications.


Thanks in advance,
Keno


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