IUBio

How long is a protein sequence?

BioSage m.j.grossman at att.net
Tue Dec 7 08:13:29 EST 2004


Hi Stefek,

The lenght of a proteins is simply determined by counting the number of
amino acid residues starting from the first, typically methionine.
However, if the protein is post translationally modified by cleavage at
the N or C terminal or in some cases a midsection is actually cleaved
out and the flanking ends are actually ligated together or a residue is
added, then the number of residues may be reported as the modified
protein length not the encoded length.

Perhaps in this case the methionine is cleaved post translationally.
Regards,

Matt
BioSage
www.biosagebiotech.com




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