IUBio

TB or not TB?

Larry Farrell farrlarr at isu.edu
Sun Jan 5 20:48:37 EST 2003


auntie_biotic wrote:

> The fact is the case at present is now in litigation.  It is clear I DO NOT
> and DID NOT HAVE tuberculosis yet the stumbling point at present is my first
> sputum.  After fifteen weeks this was found to contain M. Chelonei.
> It is  M. Chelonei that my original question was about.
> I would like an answer to this question:
> Ps If you dont answer I understand as it is a very long question
>
> All this begins in Feb 2000.
> >From the information below I would be very grateful of any thoughts you may
> have. I am the patient. I am HIV negative.
> >From one xray and the information from the TB lab report below I was
> treated for Tuberculosis then Multidrug resistant tuberculosis, then
> Micobacteria Chelonei.  I was told I needed part of my lung removed, then
> told a lung would be removed.  I was later to find in my medical
> records.  QUOTE, "Disease has spread to both lungs, we have a problem here"
> UNQUOTE
> I later gave three further sputums all of which were negative.
>
> Below are the lab reports from my FIRST sputum
>
> Specimen/Site: Sputum Lab No:
> Details: Collect date: 21/02/2000
> Authorised by:XXXXXX 23/02/2000 Received: 21/02/2000
> Appearance Mucoid Specimen
> Culture 1. 3+ Normal upper respiratory tract flora
>
> Specimen/Site: Sputum for TB Examination Lab No:
> Details: Collect date: 21/02/2000
> Authorised by:XXXXXX 12/ 04 /2000 Received: 21/02/2000
> Acid Fast Acid fast bacilli NOT seen
> Culture 1 Microbacterium species
> 2 Culture sent for reference
>
> Specimen/Site: AFB ID ( MYCOBACTERIA ) Lab No:
> Details: Collect date: 21/02/2000
> Authorised by:XXXXXX 15/05/2000 Received :12/04/2000
> Refered to Mycobacterium ref Lab
> Culture 1 Mycobacteriam Chelonei
> 2 This organism is a common enviromental saprophyte
> Dated 15/05/2000 End of Report
>
> Note how many weeks this took to become positive.
>
> >From the information given by these three microbiology reports of the same
> sputum :
>
> Question 1. From the results of this one sputum would you instigate a full
> anti Tuberculosis treatment regime?
>
> Question 2. Could it be inferred that this was a multi drug resistant strain
> of microbacteria chelonei resistant to front line TB medication?
>
> Question 3.  In context to the above sputum what does "Normal upper
> respiratory tract flora" mean?
>
> Question 4.  In context to the above sputum what does "Common enviromental
> saprophyte" mean?
>
> I gave three sputums dated 17th, 18th, 19th April 2000 all of which
> were negative.  At the time I was told they were postive.  By June I
> was told I was to have my lung removed. I stopped the medication in
> August which consisted of usual front line TB drugs plus
> ciprofloxacin 1000mg + clarithromycin 1000mg totalling 18 tabs per
> day. The doctor however still insists I have chelonei and it is a
> matter of time before I appear at hospital with symptoms.
> In August 2000 after researching on the internet I found and was seen
> by a tb expert Dr PDO Davies who said I did not need medication let
> alone
> surgery.  He said I did not have microbcterium chelonei, mdr tb or
> even ordinary tb.  He advised me to stop medication immediately.  He
> has seen me since all sputums have been negative.  It turns out the
> pains I was initially suffering from which led me to the doctors was
> costochondritis.
> ----- Original Message -----
> From: "Larry Farrell" <farrlarr at isu.edu>
> Newsgroups: bionet.microbiology,sci.bio.microbiology,sci.med.laboratory
> Sent: Sunday, January 05, 2003 11:22 PM
> Subject: Re: TB or not TB?
>
> > auntie_biotic wrote:
> >
> > > I have one "specialist saying I have tb and was treated for it whilst
> > > another told me to stop treatment.  I have since had the opinion of
> another
> > > who says the first is correct
> > > "Larry Farrell" <farrlarr at isu.edu> wrote in message
> > > news:3E18B803.FA5F4E79 at isu.edu...
> > > > auntie_biotic wrote:
> > > >
> > > > > From a sputum sample described as "Normal Upper Respiratory tract
> > > flora".
> > > > > AFB was not seen.
> > > > > The sample was cultured for TB
> > > > > Declared negative after 4 weeks.
> > > > > One month later the same sample was noted to have a microbacterium
> s.p.
> > > > > After being sent for identification and culture sensitivity it was
> > > reported
> > > > > some 5 weeks later as:
> > > > > "M. Chelonae Common Environmental saprophyte
> > > > > END REPORT."
> > > > >
> > > > > The patient is HIV negative
> > > > > I would like to ask the following
> > > > > 1.    From this sample can it be said that there is evidence of
> > > > > microbacterium infection?
> > > > > 2.    Was M. Chelonae cultured or was it already present in the
> sample?
> > > > > 3.    Has a TB organism been cultured?
> > > > > 4.    Is M. Chelonae in this setting a cause of TB?
> > > > >
> > > > > A very genuine enquiry
> > > > >
> > > > > --
> > > > > auntie_biotic
> > > > > http://www.tbandu.co.uk
> > > >
> > > > You would be much better advised to raise these questions with your
> health
> > > care
> > > > provider.  After all, *anyone* can post on newsgroups, whether they
> know
> > > > anything about the topic or not.
> > > >
> > > >
> > > > --
> > > > Larry D. Farrell, Ph.D.
> > > > Professor of Microbiology
> > > > Idaho State University
> > > >
> > > >
> >
> > At least you have had opinions from people who have knowledge of (1) the
> topic,
> > (2) your case history, and (3) your clinical/laboratory records.  What you
> get
> > here,
> > at the very best, *might* come from people with knowledge of (1) but who
> > certainly know nothing of (2) and (3).  Trying to second guess your health
> care
> > providers on the basis of information gleaned in response to a post on a
> > newsgroup is very dangerous.
> >
> >
> > --
> > Larry D. Farrell, Ph.D.
> > Professor of Microbiology
> > Idaho State University
> >
> >
>
> "auntie_biotic" <auntie_biotic at tbandu.co.uk> wrote in message
> news:ava7d1$915$1 at newsg1.svr.pol.co.uk...
> > From a sputum sample described as "Normal Upper Respiratory tract flora".
> > AFB was not seen.
> > The sample was cultured for TB
> > Declared negative after 4 weeks.
> > One month later the same sample was noted to have a microbacterium s.p.
> > After being sent for identification and culture sensitivity it was
> reported
> > some 5 weeks later as:
> > "M. Chelonae Common Environmental saprophyte
> > END REPORT."
> >
> > The patient is HIV negative
> > I would like to ask the following
> > 1.    From this sample can it be said that there is evidence of
> > microbacterium infection?
> > 2.    Was M. Chelonae cultured or was it already present in the sample?
> > 3.    Has a TB organism been cultured?
> > 4.    Is M. Chelonae in this setting a cause of TB?
> >
> > A very genuine enquiry
> >
> > --
> > auntie_biotic
> > http://www.tbandu.co.uk
> >
> >
> >

Based on the litigation, I would suggest that anyone who answered your questions
in this newsgroup would have to be completely irrational.


--
Larry D. Farrell, Ph.D.
Professor of Microbiology
Idaho State University





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