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The Drug DNP

Carlos V srcarlosvelez at hotmail.com
Thu Oct 10 01:10:14 EST 2002

This question might be a little out of the ball park for this group, but I
thought I would give it a shot.

I'm trying to do a research project on the drug DNP (Dinitrophenols) that
was perscribed in the '30s and '40s for weight loss.

This durg makes the mitochondrial membrames leaky to hydrogen ions.  (Not
being a biology major, I have to ask)  Why would a leaky mitochondrial
membrane cause weight loss?  Would that speed up the ATP production?

What were the effects of this drug?

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