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POSTDOCTORAL POSITION--MITOCHONDRIAL DNA--SEATTLE

Arnold Bendich bendich at u.washington.edu
Wed Jul 17 19:55:27 EST 2002


POSTDOCTORAL POSITION--MITOCHONDRIAL DNA--SEATTLE

  A postdoctoral fellowship is available for two years beginning after
August 1, 2002 to study the structure and replication of chromosomal DNA
molecules within plant mitochondria. We wish to determine the nature of the
'blockage' at the ends of linear mtDNA molecules: is it due to a bound
topoisomerase or some other protein involved replication, recombination or
repair, or to an unusual DNA conformation such as a G quartet? Since
blockage at the ends is a general feature of DNA extracted from prokaryotes
and eukaryotes, the work has relevance to the structure and replication of
chromosomal DNA molecules in general.
  The analytical techniques include DNA Moving Pictures, which produce
spectacular images of intact chromosomal DNA molecules as long as 100
megabases.
  These articles provide a background to the work.
    DJ Oldenburg & AJ Bendich (1998) J Molec Biol 276:745-758
    DJ Oldenburg & AJ Bendich (2001) J Molec Biol 310:549-562

Arnold Bendich
Botany Department, University of Washington, Box 355325
Seattle WA
    phone 206;685-3801
    email bendich at u.washington.edu
    FAX: 206-685-1728

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