The simple approach is to determine survivors over time in the particular
system you are studying. Usually therefore there would be several instances
of measurement but you can of course just do two; ie T=o and T= X where x
is the duration of the antimicrobial process.
It follows that T=0 log (cfu/survivors) - T=x log(cfu/survivors) =
Log(cfu/killed).
Example start of process surface A contains 1.0e6 cfu/cm2
End of process surface A contains 1.0e2 cfu/cm2
Log kill = 4 log cycles
You would account for any decline in the population not due to the
antimicrobial factor by running a control over the same time period.
Hope this helps if not email me
best Des
""Rottjakob, Dave"" <dave.rottjakob at apptecls.com> wrote in message
news:F03BBB5AFC5A9040A6D4379486806FA4466F00 at esstp.stpaul...
What is the best way to calculate log reduction?
Dave Rottjakob
dave.rottjakob at apptecls.com
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