IUBio

Stickland reaction

Emir Khatipov khatipovNO at NOuchicago.edu
Thu Aug 8 17:16:07 EST 2002


"Ecoli" <ecoli at pandora.be> wrote in message
news:T9t49.1670$Ud7.494036129 at hestia.telenet-ops.be...
> Who can tell how Gly is converted in Acetyl-P
> as a part off the Strickland reaction.
>
> If u can explain it with the reactionmechanism, that would be cool.
>
> thanks in advance,
>
>
As one of the reactions of degradation/fermentation of nitrogen compounds,
this reaction is catalyzed by glycine reductase complex, that deaminates
glycine and transfers phosphate on the remaining acetyl residue. You can
check it in e.g. Michal's "Biochemical Pathways", or "Bacterial Metabolism"
by G.Gottschalk, as well as Schlegel's General Microbiology.
Emir






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