Lactate is immeadiate source of energy for microorganism since it
directly enter in to the TCA cycle via pyruvate. It is mediated by the
L-lactate dehydrogenase (lldh). Many microorganism have membrane bound
lldh.
"Em" <ekhatipoREMOVE at midway.uchicagoREMOVE.edu> wrote in message news:<lmAv8.78$t4.1863 at news.uchicago.edu>...
> Lactate is found as one of the major carbon compounds present in sewage
> waters. There are other carbonic acids like acetate, butyrate and propionate
> that are also found in sewage. The reason why lactate is used in experiments
> is that e.g. acetate and butyrate don't support growth as well as lactate
> simply for the reason that these two compounds are much less reduced than
> lactate. Lactate as a relatively reduced compound is metabolized by
> relatively low expense for the cell, mainly via reactions of the TCA cycle,
> whereas metabolization of more oxidized acetate would require anaplerotic
> pathways (glyoxylate pathway), or, if such pathways are not present in the
> bacterium, presence of other, more oxidized, compounds (e.g., CO2 or
> artificial acceptors like DMSO).
>> Emir Khatripov
>>> ""Guha, Hillol (DERM)"" <GuhaH at miamidade.gov> wrote in message
> news:10D292F59E53D411B87300902785B0A010322CE2 at s0550007.derm.metro-dade.com..> .
> > I am seeing many research papers that use Lactate as a carbon source for
> > bioremediation. Why only Lactate, why not other carbon source? Does
> > microbes have special affinity towards lactate? If someone can throw some
> > light into the process, why lactate is used, it would be of immense help.
> >
> > Thankyou.
> >
> > Hillol Guha
> > guhah at miamidade.gov> >
> > ---
