A recent article that does a good job of explaining some of
the similarities between yeast enzymes and human enzymes, and why it
makes sense to find compounds that work on yeast enzymes while
searching for new drugs to treat humans is :
Antifungal Activities of Antineoplastic Agents:
Saccharomyces cerevisiae as a model system to
study drug action M.E. Cardenas et.al.
Clinical Microbiology Reviews Oct. 1999 pp583-611
I was impressed by the amount of mechanism of action detail the
authors included. Tom McCloud
On 30 Oct 2001 11:12:52 -0800, czhu at x-mine.com (Chang Zhu) wrote:
>Suppose we know functions of a number of yeast genes whose functions
>were not known before, what is the value of this information?
>>Could someone also point me to examples where functional studies of
>yeast genes lead to better understanding of human/plant diseases,
>especially in the area of metabolic pathways and DNA repair? Or a few
>good review articles?
>>Thanks a lot for your help.