Penicillin: A Paradigm for Biotechnology

Dr. Artem Evdokimov eudokima at mail.ncifcrf.gov
Fri May 18 10:36:00 EST 2001

If I remember correctly, early penicillin was recycled and recovered
from the patients' urine -  in the particular case that comes to mind it
was the urine of sick british policemen. It turned out that the
penicillin thus recovered was much more pure than the initial stuff
purified from the mold. Purification by Bobby.


Uncle Al wrote:
> "R. I. Mateles" wrote:
> >
> > Penicillin: A Paradigm for Biotechnology
> > Richard I. Mateles, Editor
> [snip]
> The first large scale production of penicillin was done in a
> remarkably large number of British bedpans.  When they finally went to
> submerged culture in vats the quintessential breakthrough in
> controlled addition of phenylacetic acid to make penicllin-G without
> killing the mold was made by a janitor tired of smelling cat piss
> (phenylacetic acid) everywhere.
> Let's not gild the lily.  Management has *always* been incompetent.
> --
> Uncle Al
> http://www.mazepath.com/uncleal/
> http://www.ultra.net.au/~wisby/uncleal/
>  (Toxic URLs! Unsafe for children and most mammals)
> "Quis custodiet ipsos custodes?"  The Net!

|Dr. Artem Evdokimov   Protein Engineering |
| NCI-Frederick        Tel. (301)846-5401  |
|              FAX (301)846-7148           |
|        eudokima at mail.ncifcrf.gov         |
|      http://www.ncifcrf.gov/plague       |

More information about the Microbio mailing list

Send comments to us at biosci-help [At] net.bio.net