Penicillin: A Paradigm for Biotechnology

R. I. Mateles rmateles at candida.com
Fri May 18 09:50:54 EST 2001

Penicillin: A Paradigm for Biotechnology
Richard I. Mateles, Editor

Reprints The History of Penicillin Production, the classic publication of
the American Institute of Chemical Engineers, originally published in 1970
and long out-of-print.   It is updated by the inclusion of two new chapters
dealing with scientific advances in penicillin biochemistry, microbiology,
and genetics made since 1970; and the current commercial and industrial
status of penicillin and its derivatives.

This book tells the remarkable story of penicillin's progress from a
laboratory curiosity to being the first antibiotic available for regular
use, and still a very important product today.  The contributors to this
book are the scientists and engineers who played the major role in that
enterprise, which has served as a model for fermentation development for the
last fifty years.

Among the penicillin program's "firsts,"  which continue to be important in
biotechnology today, were:

mutation and selection for microbial strain improvement
scale-up of fermentors for aerobic processes
countercurrent liquid-liquid extraction
industrial-scale lyophilization of sterile pharmaceuticals

Published: December, 1998      xi + 114 pp.     ISBN 1-891545-01-9

To order a copy, mail this form (or fax to 312-431-1605) to: Candida
Corporation, Suite 1310, 220 South State Street., Chicago, IL 60604; or buy
on-line from www.amazon.com or www.bn.com.


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Candida Corporation
Suite 1310
220 South State Street
Chicago, IL 60604

Tel: (312) 431-1601
Fax: (312) 431-1605
rmateles at candida.com

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