IUBio

Penicillin: A Paradigm for Biotechnology

Uncle Al UncleAl0 at hate.spam.net
Tue Nov 16 13:32:27 EST 1999



"R. I. Mateles" wrote:
> 
> Penicillin: A Paradigm for Biotechnology
> Richard I. Mateles, Editor
> 

[snip]

> This book tells the remarkable story of penicillin's progress from a
> laboratory curiosity to being the first antibiotic available for regular
> use, and still a very important product today.  The contributors to this
> book are the scientists and engineers who played the major role in that
> enterprise, which has served as a model for fermentation development for the
> last fifty years.
> 
> Among the penicillin program's "firsts,"  which continue to be important in
> biotechnology today, were:
> 
> mutation and selection for microbial strain improvement
> scale-up of fermentors for aerobic processes

The first scale up of penicillin production was thousands of bedpans. 
The Brits never really got a good conceptual hold on the Industrial
Revolution.

[snip]

-- 
Uncle Al
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