If you are working in an "open", as opposed to a "closed" system, you will
simply select for organisms resistant to whatever anti-infective agent you
use, particularly since Mycobacter is rather slow growing.
If you are working in a "closed" system, in which only a single organism has
been inoculated and where media and equipment has been sterilized, you need
to improve your sterile technique and/or apparatus, and thereby maintain
pure culture conditions..
Alexander Schröer wrote in message
<32c9f52b.25643166 at news.zrz.tu-berlin.de>...
>I run fermentations with a mycobacter strain which utilizes vinyl
>chlorid as carbon and energy source. Vinyl chlrorid is very toxic and
>infections with other strains where not expected.
>But since several month we have an infection with the yeast candida
>sp. which utilizes the mycobacter as carbon source :-(
>>We tried caprylate to inhibit the yeast. It worked, but the mycobacter
>strain was inhibited, too.
>>Does anyone knows another specific "antibiotikum" which does inhibit a
>yeast and not a bacterial strain ?
>>Thanks
>Alexander Schröer
>TU-Berlin, Germany
