IUBio

does penicillin (beta-lactamase inhibitors) affect viruses?

Richard P. Grant see_sig at cmtech.co.delete.uk
Wed Dec 2 03:11:48 EST 1998


In article <Pine.PMDF.3.95.981201164005.568633790D-100000 at TIGER.UOFS.EDU>,
"Patrick J. Maher" <maherp1 at TIGER.UOFS.EDU> wrote:

> As previously noted beta-lactamases destroy penicillin which is a
> beta-lactam (hence beta-lactamase).  A beta-lactamase inhibitor would then
> be something that could be taken with penicillin when treating a
> penicillin resistant infection.

And indeed, that's what clavulanic (sp?) acid is ('Augmentin')- and it
saved a pharmaceutical co. from bankruptcy, IIRC.

-- 
Richard P. Grant MA DPhil     |             rgrant at cmtech.co.uk
Senior R&D Scientist          |             work: www.cmtech.co.uk
Cambridge Molecular           |      home: www.avnet.co.uk/adastra           
                -- The Leader of the PAC --



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