IUBio

flesh-eating disease

Yersinia yersinia at CYBERNEX.NET
Tue Dec 16 22:13:55 EST 1997


John Cherwonogrodzky writes,

 Cases of the flesh-eating disease (proteolytic streptococci?) are in the 
 news recently. If the disease hits people with poor immunity, can doses 
of  Gamma Globulin (collection of antibodies from generally resistant 
population) 
prevent the disease?>

Passive artificial immunization  - the injection of antibodies made by a 
person who is immune to a disease into a person who is ill with that 
disease - was a method of treatment used against infectious bacterial 
diseases in the pre-antibiotic era. While the donor's antibodies reacted 
successfully with the pathogenic organisms, the recipients often came 
down with "serum sickness" because they produced antibodies of their own 
against the antibiodies they had received.  Perhaps it might work in  
patients who totally lack immune function (or are close to that point) - 
they probably wouldn't get the serum sickness -  but since antibodies 
have a limited life span, they might have to continue to receive 
injections of donor antibodies until the infection was neutralized.

Good question, this is really interesting. Does anyone out there know if 
any studies have been done with passive artificial immunization in AIDS 
patients?

Infectionately,
Yersinia.

"Van der waals with boughs of holly..."




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