Here is one reference:
Subject: HIB VACCINE CAN CAUSE HIB
X-UIDL: b3b21cd824e090b869ccfa181e86c886
Haemophilus influenzae; "Haemophilus influenzae Type B Meningitis in
the
Immediate Post-Immunization Period Consequence or Coincidence."
Source: Vaccine Weekly
According to the authors' abstract of an article published in Archives
de
Pediatrie, "BACKGROUND: The introduction of vaccines against
Haemophilus
influenzae type b (Hib) has had a substantial impact on Hib
infections.
Their use has established their excellent safety profiles but
occasional
adverse effects have been reported. CASE REPORT: A 4 month-old infant
was
admitted for a severe form of Hib meningitis with septicemia whose
first
manifestations developed 3 hours after the first immunization with a
conjugate vaccine against Hib (PRP-T). The outcome was good without
any
sequelae. DISCUSSION: A dramatic decrease in serum antibodies
due to antigen-antibody reaction during the first days after
immunization
has been reported; this mechanism and some epidemiological data could
favor
the hypothesis that the vaccine is responsible for the infection, at
least
the unconjugated vaccines. CONCLUSION: Any fever occurring in the
immediate
post-immunization period must alert the possibility of a Hib
infection." The
corresponding author for this study is: D Floret, Univ Lyon 1, Hop
Edouard
Herriot, Unite Reanimat Pediat, Pl Arsonval, F-69437 Lyon 03, France.
For
subscription information for this journal contact the publisher:
Editions
Scientifiques Elsevier, 141 Rue Javel, 75747 Paris Cedex 15, France.
AUTHORS: Basson, E.; Dimaio, M.; Stamm, D.; Cagnin, S.; Berger, C.;
Floret, D.
SOURCE: Archives de Pediatrie, April 1996;3(4):342-344.
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Also, our small group has received several reports of serious
reactions from the Hib vaccine - including two instances of children
developing laboratory-diagnosed Hib following administration of the
vaccine.
I hope this helps. Please feel free to contact me if you would like
more information.
Meryl Dorey
botta at uniud.it (Giuseppe Botta) wrote:
>I am interested for my thesis in getting information on efficacy and
>safety of different vaccines against H. influenzae. Can you help me?
Vaccination Awareness Network, NSW (066) 871-699 phone
P.O. Box 177 (066) 872-032 fax
Bangalow NSW 2479 van at mypostbox.com
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