I have a bit of a challange coming up. I am doing some specialty testing for
a person that is working with a topical gel that contains Gentamycin and
Promomycin and is going to want a Preservative Effectiveness test ran on it.
I have looked through several books in an attempt to find a neutralizer
for these compounds. I am also going to do some membrane filtration
studies looking at bioburden and general sterility, nothing "regulated"
yet but I am sure that is coming. Can somebody help me with a
neurtalizer approach to this? I am going to try to get the gel into a
suspension using saline and tween 80 and rinse it with Fluid D after
filtering and think that that might work. The obvious problem is that
when I do an APE test on it I can't rinse out the active ingredients.
Thanks in advance,
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Ronald Gerth The University of Iowa
Public Health Microbiologist Hygienic Laboratory
Internet: rgerth at uhl.uiowa.edu
Phone: (319) 335 4500 Fax: (319) 335 4555
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