I have posted a few times before about
a new group bionet.molbio.recombination
that I will be proposing soon....
Here is the rough proposal... if you have any comments please
send them!!!!
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Proposal to establish RECOMBINATION/bionet.molbio.recombination
Proposed USENET name: bionet.molbio.recombination (unmoderated)
Proposed mailing list name: RECOMBINATION
Proposed e-mail addresses: recom at net.bio.netrecom at daresbury.ac.uk
Discussion leaders:
Graham Dellaire, e-mail: popa0206 at po-box.mcgill.ca (b2xe at musicb.mcgill.ca)
Department of Medicine (Div. of Exp. Medicine), McGill Univeristy,
Montreal, Quebec, Canada
George Szatmari, e-mail: szat at ere.umontreal.ca
Tentatively
Denis Cournoyer (Mcgill Experimental Medicine) (gene therapy)
Terry Chow (McGill): e-mail MDTY at Musica.mcgill.ca
(mammalian genetics)
Charter:
The purpose of the RECOMBINATION newsgroup is to provide a proper
forum for the discussion of issues pertaining and involving recombination
of DNA or RNA, in its many forms (see _Topics of Discussion_). Primarily
it should enable those researchers who work in recombination or aligned
fields to communicate ideas and information, as well as, provide a chance for
collaboration among national and international research groups.
Topics of Discussion include:
1. Gene conversion and ectopic integration
2. Genome accessibility and nuclear/chromosome structure and recombination
-Matrix attachment sites (MARS)
-nucleosomes, histone 1
-recombination hotspots
-fragile sites
-origins of replication
3. Effect of DNA topology on recombination (Triple strand, Z-DNA, cruciform, bent etc)
4. Homologous recombination vs. nonhomologous or illegitimate
-comparisons between bacterial, yeast and higher eukaryotic recombination
systems (ex. fungi, mammals)
5. Models of recombination (One-end invasion, Double strand Break Repair, SSA etc)
6. Site-specific recombination systems (invertase, Cre and Flp recombinase etc)
7. Specific recombination systems in complex organisms
-VDJ recombination
-Antigenic variation and recombination (ex. trypanosomes, HIV, N.gonorrhea)
-Yeast mating type locus
8. Transcription and recombination
9. DNA replication and recombination (ex. gene amplification (DHFR etc))
10. Evolution of the Genome
-retroposons (Line-1, Sine's), retroviruses and transposons
-formation of gene clusters and comparative mapping
-recombination between other repeat elements (alpha satellites, telomeres)
11. DNA repair systems and recombination (DSB and mismatch repair)
-including DNA repair deficient diseases (ex. Xoderma Pigmentosum)
12. Applications of recombination
-Gene therapy
-Transgenics and gene transfer
13. Viral diversity through RNA recombination
14. Population genetics and recombination:i.e. as a source of allelic variation
and as a measure of genetic exchange within and between populations.
In addition this newsgroup provides:
A forum for the exchange of information about future congresses
and meetings in areas of molecular biology relating to recombination
A forum for the exchange of information about textbooks, internet
resources, visual materials, and computer programs.
A source of quick help for last-minute troubleshooting, sources of materials,
and practical advice; in areas such as
-Vector design for transgene experiments
-Gene transfer techniques
-Animal models and cell lines
-Gene therapy protocols
Subscribers are welcome. Contributions within the functions outlined
above are encouraged.
The newsgroup is unmoderated.
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_______________________________________________________________________
Graham Dellaire Snail Mail:
Red Cross, Research
McGill Univeristy Montreal Blood Services
Faculty of Medicine 3131 Sherbrooke St. East
Div. of Experimental Medicine Montreal, QC, Canada
E-mail: popa0206 at po-box.mcgill.ca H1W 1B2
B2XE at musicb.mcgill.ca
Fax: (514) 525 0881
Voice: (514) 527 1501 ext 175
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