Hello,
Does anybody know of a broad-spectrum antibiotic or anti-fungal agent
which will not affect platelet aggregation? I've conducted an experiment
which requires me to leave a relatively rich "platelet suspension buffer"
(which is an isotonic HEPES-buffered phosphate buffer with dextrose and
albumin) under non-sterile conditions at 37 deg. C for a few days. It
turns into a cloudy solution after a day or two, looking suspiciously like
bacterial colonization. I then need to take the buffer and use it for
platelet aggregation tests. I've seen a citation in the literature (don't
have it handy right now) which mentions an antibiotic with minimal
effect on platelets, but it's bacteriostatic against only a few
exotic-sounding strains.
Please reply by e-mail; I don't read bionet.microbiology much.
Thanks for any help in advance.
--
Marc Takeno takenomm at u.washington.edu
