IUBio

Please help.....

John Nash nash at nrcbsa.bio.nrc.ca
Wed Oct 19 09:08:07 EST 1994


In article <3826vt$o6t at aggedor.rmit.edu.au>,
Manila <s933180 at minyos.xx.rmit.EDU.AU> wrote:

>	Hi everyone.... well ... actually I am just get into the
>microbiology field .... there are some problems that I could not answer,
>could someone please give a bit  of spare time to help me....

>	Question 1:
> Using examples, discuss, the mechanisms by which microoganisms damage
>host tissues.

Find a good book on bacterial pathogenesis - try "Bacterial
Pathogenesis: a molecular approach" by Salyers and Whitt; published by
ASM press.

>	Question 2 :
>	The development of resistance in bacteria is an undersiable
>consequence of the use of chemotherapeutic agents.
>	Discuss the nature, incidence and significance of acquired resistance
>and the mechanisms used by bacteria to develop resistance to the B-lactam
>and aminoglyciside antibiotics.

Should be in any standard microbiology texts.  Usually a whole chapter
is dedicated to it.  <Hint, look up "plasmid", or "R-factor", or
"transposon".>

>	Question 3:
>	Transposition involves the movement of transposons from one region in
>a genome to another site or another genome.
>	Discuss the mechanism of transposition and the genetic
>organisation of transposons which allow them to undertake this mobility.

Most standard genetics texts cover this.  <hint: look up "insertion
element" as well as transposon>

>	Question 4:
>	Describe the process of generalized and specialized transduction
>with reference to temperate phage. How do these phage differ from lytic
>phage?

Even the old standard genetic texts cover this.

The following is not a flame, but some well-meant advice.

This newsgroup is for the discussion of ideas in microbiology. The net
is a valid, useful, and often imaginative source of wonderful new
ideas, and some old ones.  Its use is to be encouraged strongly.  We
often give people hints, ideas and suggestions for theses and
projects, but I would rather that we don't do peoples' take-homes for
them, especially questions covered by books found in most university
libraries.  Many of the participants teach, and certainly I would get
upset if a netter were to do a student's take home for him/her.  Your
prof may be reading this thread now.

I know that RMIT has a good library and if you can't find a good
microbiology text book there, try Monash or Melbourne Unis.  As a last
resort, ask your prof if you can borrow his book.

john
-- 
John Nash                          | Email: nash at nrcbsa.bio.nrc.ca
Institute for Biological Sciences  | http://cansnd.cisti.nrc.ca/~nash/home.html
National Research Council of Canada|  for an eclectic collection of
All opinions are mine, not NRC's!  |  WWW molbio and other services.



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