IUBio

sporulating GNR

John Bowman jbowman at utkvx.utk.edu
Mon Nov 14 12:42:41 EST 1994


In article <Pine.SOL.3.91.941110122850.22688B-100000 at isnet> bmorrell at ISNET.IS.WFU.EDU (Bob Morrell) writes:
>From: bmorrell at ISNET.IS.WFU.EDU (Bob Morrell)
>Subject: Re: sporulating GNR
>Date: 10 Nov 1994 09:52:57 -0800

>On 10 Nov 1994 PWILLIAM at lear.sinclair.edu wrote:

>> A colleague read about a soon-to-be-released book by Laurie Garrett,
>> "The Coming Plague", which claims that strains of E. coli, V. cholerae, 
>> and Legionella are able to undergo sporulation. 

>Old work performed at Rita Colwell's lab at the Univ. of Maryland suggest 
Vibrio (at least) can form viable but apparently non-cultivable forms which 
apparently are likened to spores. From what I've read genes encoding 
spore formation, i.e. spo genes (or least homologs of them) have been detected 
in E. coli and Vibrio spp. but they do not seem to be expressed under 
"normal" growth conditions. In any case spores can come in many different 
forms with various degrees of "toughness". In terms of public health, the 
spores of such bugs as Bacillus anthracis (anthrax) and Clostridium botulinum 
(botulism) are the biggest concern.


John Bowman, Univ. of Tennessee, Knoxville



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