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cefachlor - what is it?

Pfaller Peter pfaller at mpk.med.uni-muenchen.de
Wed Dec 7 10:58:14 EST 1994

In article <3c2vub$p91 at feedback.eng.umd.edu>, hortense at Glue.umd.edu (Frame
Ok) wrote:

  The antibiotic 
> has been switched to cefachlor, and has improved the patient's condition.
  could someone briefly tell me what 
> sort of antibiotic it is, and how it works?
> thanks a lot...
> /meagan

Hi Meagan,

cefachlor is a oralcephalosporine and a member of the cefalexin-group.
The spectrum is partial similar to that of cefazolin, but its activity is
a bit  weak, especially against gramnegative rods.
Parts of E. coli and klebsiella and proteus strains are resistent.
Cefaclor is bacteriostatic against haemophilus influenza (ampicillin
susceptible strains) dosis: 1,6-3,2 mg/l, and ampicillin resistent strains
dosis: 3,2-6,4 mg/l.


Peter Pfaller
Inst. fuer Med. Mikorbiologie
Klinikum Grosshadern
Tel 089/70954048
pfaller at mpk.med.uni-muenchen.de

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