Raymond Tsang (rtsang at hpb.hwc.ca) wrote:
: I am looking for a condition to grow up Salmonella strains that favours
: temporarily the production of only low numbers (e.g. one) or even no
: O-specific side chains in their lipopolysaccharide.
Sounds like you want to make the strain rough. Prolonged storage on
media with a high sugar content would do the job. However, since this
roughness is determined chromosomally, it would be very difficult, if not
impossible to get the strain smooth again.