Judging seq. similarity??E-mail addr. included.

campanelli lab campanll at ottawa.scs.uiuc.edu
Tue Nov 12 17:00:18 EST 1996

I'm pretty statistically ignorant. What are some good rules to use in
comparing two aligned sequences similarities or percent identities with
a randomized version of one. For example, two sequences have 34%
sequence identity in a pileup. After randomizing one of the sequences
this falls to 15%. What is a good way to judge the significance of this?
Any references would be appreciated. Thanks.

Steve Johnson
Univ. of Illinois

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