I'm pretty statistically ignorant. What are some good rules to use in
comparing two aligned sequences similarities or percent identities with
a randomized version of one. For example, two sequences have 34%
sequence identity in a pileup. After randomizing one of the sequences
this falls to 15%. What is a good way to judge the significance of this?
Any references would be appreciated. Thanks.
Steve Johnson
Biochemistry
Univ. of Illinois
