You could try using the GCG program REVERSE, which will allow you to reverse,
complement or reverse-complement your sequence and save it as a new file.
Dr Mathew Woodwark mathew.woodwark at bbsrc.ac.uk
Molecular Biology Software Support Tel: 01582 762271
BBSRC Computing Centre Fax: 01582 761710
West Common, Harpenden
Hertfordshire, AL5 2JE, UK