R. Doelz wrote recently:
....
>> We have seriously investigated this earlier and concluded that the
> work done by many of the 'casual' users (i.e., type in sequence, search
> sequence, retrieve top hit) can indeed be done by networked databases.
> However, to the residual 30% of users, who do not stop after having noticed
> merely insignificant hits, what happens if (1) you need to search
> for subsets in the database, (2) you need _many_ database entries
> (i.e., a 100 or 1000) and (3) you do many comparisons, statistical or
> evolutionary analysis, and individual work which should be done anyhow
> after a reasonable search.
>......
>> How would you imagine to run this type of search in a networked environment?
>
I'd like to say that I agree 150% with Reihardt. Think, for example, how useful
is DATASET in GCG (the ability to build your own private database).
For years now, I've never been able to understand how people who spent months
or years to sequence something can be satisfied with a mere BLAST search
performed in 2 seconds. Well, in fact that's good to me: I can try to extract
something interesting from YOUR sequences ...
Cheers,
Jean-Loup
