kzhao at BIOVX1.BIOLOGY.UCLA.EDU wrote:
>> Lou Hom wrote on June 11:
>> In Alberts, they say that the initial attachment of the 14-sugar complex to
> Asn's in the ER happens rapidly . . . something like "most proteins are
> glycosylated as they are translocated". Anyway, the important part was the
> "most" -- does anyone have an idea what "most" means? Does it have to do
> with kinetics or selectivity or both?
> ___________________________________________________________________________
>> Dr. Barbara Imperiali, a chemistry professor at CalTech extensively studied
> the mechanism of N-glycosylation by using synthetic inhibitors to oligo-
> saccharyltransferase, the enzyme that en bloc transfers GlcNAc2Hex12 from its
The netOglyc v2.0 server predicting Mucin type O-glycosylation sites
in mammalian proteins as described in:
NetOglyc: Prediction of mucin type O-glycosylation sites based on
sequence context and surface accessibility
J.E. Hansen, O. Lund, N. Tolstrup, A.A. Gooley, K.L. Williams and S.
Brunak. Glycoconjugate Journal 1997, in press.
available at http://www.cbs.dtu.dk/services/NetOGlyc/
have now been updated with automatic graphics output
in both gif and postscript format
with regards
Jan Hansen
Center for Biological Sequence Analysis
Department of Chemistry
The Technical University of Denmark
Building 206
DK-2800 Lyngby
Denmark
Phone: +45 4525 2485
Fax: +45 4593 4808
E-mail: janhan at cbs.dtu.dk
WWW: http://www.cbs.dtu.dk/janhan/homepage.html
