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colostrum sialyltransferase

Roy Jefferis r.jefferis at bham.ac.uk
Wed May 1 13:30:59 EST 1996

In article <31813D8E.71D0 at irl.cri.nz>, R.Furneaux at IRL.CRI.NZ (Richard Furneaux) says:
>I was having a first look at the Glycoscience Newsgroup, and came across an interesting 
>question from Martin Dalziel regarding the role of secreted transferases.
>We have been working on the sialyltransferases in bovine colostrum.  What puzzles me is 
>that sialy(2,3)lactose and sialyl(2,6)lactose are present at similar amounts in 
>colostrum, yet only the sialyl(2,6)transferase activity is present when monitored using 
>lactose acceptors.  Why would the enzyme responsible for the 2,3-lnked trisaccharide be 
>essentially absent?  Or perhaps the question is why would the 2,6-transferase be 
>released while the 2,3-transferase is not?
>Martin...did you receive any worthwhile responses?
>Richard Furneaux
>Industrial Research Limited
>New Zealand

Sorry to disappoint but I am using this to get myself hooked into the 
Newsgroup. I am Si Dong and I have just started working with Roy Jefferis.
We are looking at control of IgG glycosylation. 
Hope to talk to people later.Si 

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