IUBio

Lotus lectin recognize core fucose?

phillip buckhaults buckhaults at bscr.cc.uga.edu
Fri Sep 15 16:00:24 EST 1995


In article <christer.ericsson-0609951052010001 at drop-dead.cmb.ki.se>,
christer.ericsson (Christer Ericsson) wrote:

> I am trying to identify N-linked glycoproteins carrying alfa 1 to 3-linked
> fucose on the chitobiose core. Will Lotus tetragonolobus lectin recognize
> this determinant? Suggestions for a better choice of lectin?
> 
> Christer
> 
Christer,
i am not an expert on this lectin but i believe it recognizes the
abovementioned linkage in the context of a complex chain. 
core-fucosylated high mannose or hybrid types may not bind.

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