In article: <496ti5$bk0 at dux.dundee.ac.uk> (k.c.breen at dundee.ac.uk) writes:
>> I was wondering if there are any commercially available inhibitors of
> terminal
> glycosyltransferases (specifically sialyltransferase and
> galactosyltransferase).
> In particular, I am interested in agents which can be used to treat cells
> in
> order to subtly alter their protein glycosylation patterns. I have tried
> mannosidase inhibitors, but these act at an early stage in oligosaccharide
> elongation and processing to prevent the transfer of a number of terminal
> sugar residues
>Would Tunicamycin be of any use in this case ?
--
Craig Webster | Tel: 01245 442700
Grade B Clinical Biochemist| Fax: 01245 514077
Broomfield Hospital | email (work) cwebster at broombio.demon.co.uk
Chelmsford, CM1 5ET | (home) cwebster at bimbo.demon.co.uk
