Posted on behalf of Prof. Nigel Jenkins:
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De Montfort University
School of Applied Sciences
Ph.D. Studentship in
Molecular Biotechnology
Studying the alternative glycosylation pathway1 in genetically modified
animal cells used for the manufacture of recombinant proteins. The project
will provide a training in cell culture, glycoprotein analysis, and some
molecular biology techniques. The student will join the research team of
Prof. Nigel Jenkins2,3 and enquiries can be addressed to him on 0116 257
7118 ,or email njenkins at dmu.ac.uk
Candidates should hold, or expect to obtain at least a 2:1 Honours Degree in
Biochemistry or Cell Biology, and fulfil the other BBSRC eligibility
requirements (British citizenship or residence in UK for 3 years).
Applications enclosing C.V. should be sent to the School of Applied
Sciences, De Montfort University, Leicester LE1 9BH by 26th June.
Starting date is 1st October 1995. Stipend stlg6,500 p.a.
1. Villers, C., Plancke, Y., Cacan, R. and Verbert, A. 1994. Rapid detection
of the alternative N-glycosylation pathway using high pH anion-exchange
chromatography. Glycoconjugate J. 11:226-231.
2. Jenkins, N. 1995. Monitoring and control of recombinant glycoprotein
heterogeneity in animal cell cultures. Biochem. Soc. Trans. 23:171-175.
3. Jenkins, N. and Curling, E.M. 1994. Glycosylation of recombinant
proteins: problems and prospects. Enzyme Microb. Technol. 16:354-364.
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Does anyone know details about the enzyme responsible for conversion of
N-acetyl to N-glycolylneuraminic acid? Has it been cloned, if so has anyone
got the cDNA?
email njenkins at dmu.ac.uk
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Thanks Iain
Prof. Nigel Jenkins
njenkins at dmu.ac.uk
School of Applied Sciences
De Montfort University
Leicester LE1 9BH, U.K.
Tel:++116 257 7118
Fax:++116 257 7287
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Iain Wilson Institut fuer Chemie
Tel: 43-1-47654-6065 Universitaet fuer Bodenkultur
Fax: 43-1-310-5176 Gregor-Mendel-Strasse 33
E-mail: wilson at edv1.boku.ac.at A-1180, WIEN, Austria
