In article <3mb11c$amj at io.salford.ac.uk>, R.Lauder at lancaster.ac.uk (Bob Lauder) says:
>>In article <3lrio2$ig6 at news.duke.edu>, srps at galactose.mc.duke.edu (Steven Pirie-Shepherd) says:
>>>>I need to know the structure of the tetrasaccharide sialyl Lewis ^x. I
>> NeuAc(alpha2-3)Gal(beta1-4)GlcNAc(alpha1-3)Fucose.
>
I have been criticised for the way I have written this structure. It
may be more clearly represented by:
.................Gal(beta1-4)(Fucose(alpha1-3))GlcNac
This shows that the fucose is alpha1-3 linked to the GlcNac
residue as a branch, and not as part of the chain.
I have also been critisised for my representation of N-acetyl-neuraminic
acid as NeuAc and not NeuNAc. It is possible that a reader may not clearly
derive information regarding the fact that the acetyl group is N-linked
and not O-linked.
Therefore the structure for sialyl Lewis ^x may be represented by:
NeuNAc(alpha2-3)Gal(beta1-4)(Fucose(alpha1-3))GlcNac
or
Neu5Ac(alpha2-3)Gal(beta1-4)(Fucose(alpha1-3))GlcNac
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Bob Lauder R.Lauder at lancaster.ac.uk
Division of Biological Sciences Tel +(44)(0)1524 65201
Lancaster University, Lancaster, UK Fax +(44)(0)1524 843854
