Alexey G. Novoradovsky, Ph. D.
ADDRESS: 1001 Rockville Pike, Apt. 1114. Rockville, MD 20852.
home phone: (301)309-6532; work phone: (301)443-9274
e-mail: alexey at helix.nih.gov
1976-1981 Department of Biological Anthropology
Moscow State University, Moscow, Russia
1992-Research Scientist holding a "Fogarty Visiting Associate" position from the National Institutes of Health.
Molecular genetic and population genetic study of human mitochondrial aldehyde dehydrogenase (ALDH2) polymorphism. Study of human microsatellites as genetic markers for linkage analysis of alcoholism and relative traits. Search for trinucleotide tandem repeats amplification (DNA expansion) in human diseases.
1987-1992 Senior Research Scientist in the National Research Center of Medical Genetics, Academy of Medical Sciences USSR(Moscow).
Gene marker association study of common diseases in human populations.
Micro-evolutionary survey of human populations, study of genotype-environmental interactions in health and disease.
Prenatal selection study in humans by the research on placental alkaline phosphatase (PLAP) polymorphism.
1981-1987 Junior Research Scientist in the Institute of Anthropology, Moscow State University.
Population genetic and gene-geographic research of Russian human populations.
Developing of simplified semi-micro modifications of gel enzyme electrophoresis, for the phenotyping of protein genetic polymorphisms adapted for large-scale population screening.
Molecular Genetic:Nucleic acid extraction and purification from human and animal tissues; RFLP, blotting techniques; PCR, RNA-PCR, primer allele specific amplification (PASA), single strand conformational polymorphism (SSCP) and relative methods; DNA sequencing, automatic sequencing; PCR-genotyping of short tandem repeat polymorphisms (STR) using multicolor fluorescent technicues on Model 373A DNA Sequencer (Applied Biosystems), Repeat Extension Detection (RED).
Biochemical and Genetic: Gel electrophoresis, isoelectric focusing, thin-layer and column chromatography, enzyme assays, phenotyping of biochemical genetic markers, blood groups and serum immunoglobulin (Gm, Inv) typing.
Study of blood oxygen transport function.
Biostatistical methods in the population genetics; linkage analysis; database operating on the programming level.
1987 - Ph.D. in Biology. Moscow State University, Scientific Board of Physical Anthropology. Thesis: "Anthropological Aspects of the Study of High-Altitude Human Populations of Pamir".
REFERENCES, LIST OF PUBLICATIONS: Available upon request.