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LOD = 0.0 at all theta ???!!!

Mike Morris mike at medsun.unige.ch
Mon Nov 15 11:21:41 EST 1993


  Hi - I hope somebody is still reading this group.

  I have just run a 2 point linkage on a 60-member family, with disease
plus 1 four-allele marker, on LINKAGE 5.2 on a Sun. The data was very
informative, with perfect linkage.
  MLINK with theta from 0-0.5 (inc = 0.05) gave LOD 0.0 at _all_ values!!
  LODSCORE also gives LOD of 0.=.

  Our configuration usually works, but I have not run "bigger" than about
individuals before. Any ideas where the problem (bug?) lies?.

tia,
	Mike

*******************************************************************
Mike Morris PhD               * *
Division of Medical Genetics  * *  tel (Switzerland) (22) 702.56.94
University of Geneva          * *  fax (Switzerland) (22) 702.57.06
Geneva                        * *        email mike at medsun.unige.ch
Switzerland                   * *
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