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Increasing Parameters

Peter Woollard x3296 pwoollar at crc.ac.uk
Tue Sep 10 08:36:40 EST 1991


Is it a general trend that linkage analysis problems are getting
larger and requirements for memory exponentially increasing?

Will the developments in mapping technology such as the use of
microsatellites produce data with more and more alleles, (eg. 20
and beyond)?

With Lathrop & Lalouel's linkage analysis package (version 5.1),
we already considering increasing the number of alleles from the
defaults [currently 5 to 12 alleles depending upon the program]
up to 20.

Have the authors of the above package ever considered converting
over to C for the next release and also using dynamic memory
allocation? (The latter would save having to recompile the
programs,  everytime a problem with different requirements is run.)

I would be interested in any comments or ideas.


Peter Woollard

Computing Services Section,
MRC-Clinical Research Centre and            Internet: p.woollard at crc.ac.uk
Human Genome Mapping Project Resource Centre   Janet: p.woollard at crc.ac.uk
Watford Rd, HARROW, Middx, HA1 3UJ, U.K. EARN/Bitnet: p.woollard%crc at ukacrl
Tel 081-869 3296    Fax 081-423 1275     Usenet: ...!mcsun!ukc!mrccrc!P.Woollard

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