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Question about Phosphoglycerate mutase (PGM) mechanism

Davit Hakobyan davhak2000 at hotmail.com
Wed Jun 9 03:13:20 EST 2004


Hi All,

In glycolysis the phosphoglycerate mutase (PGM) converts 3PG into 2PG.
As it appears the phosphorylated HIS residue (8) "gives" its PO3 to
3PG and some B element (probably Boron) takes the Hydrogen atom, which
have been previously bound to the oxygen of the second carbon (C2). My
question is what is this B element, which takes the hydrogen ?
Is it really a Boron ? Because I have couple yeast PGMs (downloaded
from Protein Data Bank site) and they do not have any Boron atom.
The PGM i'm interested the most has its ID 1QHF at PDB (and no Boron
(B) atom).

Thanks for any help.




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