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2. Announcement: 1st Internationl Symposium on ESCEC

Carsten Kettner carsten.kettner at arcor.de
Fri Jul 18 03:04:40 EST 2003

	It is a pleasure of the Beilstein-Institut to announce the 1st
International Symposium on Experimental Standard Conditions of Enzyme
Characteriaztions, to be held at Ruedesheim/Rhine, Germany, Monday
October 6th to Wednesday October 8th, 2003. Further information is
available at
Registration is open until August 31st. Please note, that, due to a
fruitful atmosphere for discussions, the number of participants is
limited to max. 70 persons.

	Functional characterization of enzymes and the subsequent
computational analysis and modelling of the cellular metabolism and
the interaction of cells within tissues and organs led to the
foundation of a new branch within the life sciences, called systems
biology. At this time, data from metabolic simulations show broad
value ranges with high uncertainty because the accessible experimental
data have been generated under non-standardized experimental
conditions. The results from functional characterizations of enzymes
are usually determined by individual laboratory-specific application
and implementation of the experimental design. Thus, successful
biological analysis requires comparable and reliable data from both
enzyme and physiological interactions collected under standardized
experimental conditions. However, as long as the quality of the in-put
as well as the out-going modelling data can not be improved, the
chances of success for this young discipline to escape from the
verbally overused -omics-sciences are poor.

Following speakers will address questions such as
- are any standards used in the field of functional 
characterization of enzymes?
- Do current repositories for enzyme characterization data meet the
demands of users?
- Which data types for metabolic simulations are necessary?

Rolf Apweiler, EBI, UK
David Fell, Oxford Brookes University, UK
Jan-Hendrik Hofmeyr, University of Stellenbosch, South Africa
Hans-Georg Holzhütter, Charite Berlin, Germany
Pedro Mendes, Virginia Bioinformatics Institute, USA
Dietmar Schomburg, Universitaet Koeln, Germany
Stefan Schuster, Max-Dellbrueck-Center, Berlin, Germany
Hans Westerhof, BioCentrum Amsterdam, The Netherlands
Minoru Kanehisa, Kyoto University, Japan
Mark Poolman, Oxford Brookes University, UK
Herbert Sauro, Caltech Pasadena, USA
Keith Tipton, Trinity College, Institute for Neuroscience, Dublin,
Detlev Kroemker, Fraunhofer Institut AGC, Frankfurt/Main, Germany
Hanno Langen, Hoffmann-LaRoche, Basel, Switzerland
Jacky Snoep, University of Stellenbosch, South Africa
Alisdair Fernie, Max-Planck-Institut, Golm, Germany

If you need further information about the symposium and/or process of
registration, topics, scientific topics, please do not hesitate to
contact me: ckettner at beilstein-institut.de

With best regards,
Carsten Kettner

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