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reverse patchclamp?

Morgan Ryan morgan at mercury.interpath.net
Wed May 4 21:26:43 EST 1994


Can patchclamping be used to _introduce_ molecules into a cell? (Sorry, 
I'm not a scientist,just curious). Could it be used to gently inject some 
choice molecules into the cell to see what the regulatory response is? 
Biochem texts always have lots of problems like "what would happen if the 
amount of DHAP went up by ten times?" Well, what _would_ happen? Could 
you use patchclamping to find out without bashing a cell? Morgan



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