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[Bionews] Course on Bioinformatics and Functional Genomics of Insect Vectors

Worachart Sirawaraporn scwsr at mucc.mahidol.ac.th
Sun Jul 10 22:06:21 EST 2005

2nd Training Course on Bioinformatics and

Functional Genomics Applied to Insect Vector of Human Diseases


Sponsored by UNICEF/UNDP/World Bank/ WHO Special Programme for Research =
and Training in Tropical Diseases (TDR)


Organized by

Center for Bioinformatics and Applied Genomics (CBAG) and

Center for Vector and Vector-Borne Diseases (CVVD)

Faculty of Science, Mahidol University, Bangkok, Thailand

September 19-30, 2005


Call for Application



            The completion of the Anopheles gambiae genome and genomes =
of other vectors of medical importance have provided unprecedented =
opportunities for scientists to study vector-pathogen interactions that =
are central to disease pathogenesis and treatment.  Through integration =
of advanced and high throughput gene expression technologies, the =
processes of identifying new antigens and new drug targets could be =
accelerated and hence morbidity and mortality caused by vector-borne =
diseases could be reduced.  The training course on bioinformatics and =
functional genomics applied to insect vectors of human diseases is part =
of the activities of RCS-Plus of WHO/TDR to strengthen the research =
capacity of scientists from disease-endemic countries (DEC) and to =
develop their skills in exploiting genome data of insect vectors, =
parasites and hosts through the application of bioinformatics and =
post-genomics tools in molecular entomology research.=20

            The training course is an initiative of R&D Research =
Capability Strengthening (RCS-Plus) jointly supported by the TDR =
Research Capacity Strengthening (RCS) unit and the Molecular Entomology =
Committee (BCV)/Basic Strategic Research (STR) unit.  The main objective =
is to strengthen research capability and to train young scientists from =
DEC on bioinformatics and applications of current post-genomics tools in =
the study of insect vectors of medical importance.


About the training course:

            This will be a 2-week training course with lectures, =
hands-on and/or demonstrations.  Emphasis will be placed on the current =
knowledge of molecular entomology and genomic approaches to study =
vector-host-pathogen interactions, and exploitation of computational =
tools and advanced cutting-edge technology for the study vector genomes. =
 The course will consist of lectures and theoretical sessions in the =
morning and hands-on sessions in a computer laboratory in the afternoon. =
 Time will be allocated in the evening to follow-up the course contents =
and to do some scripting exercises.  Each participant will be provided =
with a computer during the training course.  The selected participants =
will receive training materials and documents on the main topics =
covered.  At the end of the course, the participants will be asked to =
evaluate the training course and the facilitators.  The participants =
will occasionally be followed-up with respect to their achievements from =
the training course upon return to their home country.


Objectives of the course:

            The objectives of this training course are: 1) to train =
individuals in the use of computational tools for searching and =
analyzing genomes of vectors of medical importance; and 2) to develop a =
sustainable research network focused on the applications of =
bioinformatics and functional genomic approaches to study vectors and =



            Advanced PhD students, postdoctoral fellows and young =
faculty members who are active in entomological research and are working =
on insect vectors causing diseases of medical importance and have plans =
to apply bioinformatics and post-genomics tools for their future =
research are highly encouraged to apply.


Criteria for Selection:

            Fifteen participants (preferentially from Asia and Southeast =
Asia) will be selected from the applications received.  Followings are =
the selection criteria that the selection committee will strictly =

=C2=B7        Good biochemistry and molecular biology background

=C2=B7        Demonstrated computer skills and ability to use basic =
bioinformatics tools

=C2=B7        Fluent in English

=C2=B7        Involvement in entomological research preferentially =
insect vector(s) causing diseases of TDR portfolio (see =
http://www.who.int/tdr/ for more details)=20

=C2=B7        Provision of applying the training skills for research in =
home institution

=C2=B7        Available for the entire duration of the course


Course Contents:

            Follows are provisional topics to be included in the =
two-week training course:=20

=C2=B7        Bioinformatics and computing network: an overview

=C2=B7        TDR-pathogens and vector genomes, fundamental of =
genome/genome sequencing

=C2=B7        Important databases, database retrieval tools and data =
evaluation and data analysis

=C2=B7        Introduction to EMBOSS Package

=C2=B7        Genome comparison, functional annotation and annotation =

=C2=B7        Gene prediction and gene prediction tools

=C2=B7        Sequence alignments, molecular evolution and phylogenetic =

=C2=B7        Genes and genome organization of insect vectors, genetic =
maps and physical maps

=C2=B7        Expression system and transposable elements in insect =

=C2=B7        Molecular biology of endosymbionts, pathogens and =
parasites transmitted by insect vectors, insect vector-human =
host-microbe interactions

=C2=B7        DNA microarrays, applications for research on vectors, =
hosts and pathogens

=C2=B7        Proteomics and functional genomics analysis of vectors and =

=C2=B7        Transgenic vectors, transformation methodologies and =
potential applications

Course Website: =

Application Procedure:

            The applicants MUST complete the application form which is =
available at the course website.  All applications MUST BE submitted =
ONLINE (paper application will not be accepted).  The deadline for =
submitting the application is August 5, 2005. Two reference letters =
(scanned letters with letter-head and signatures) from supervisors =
and/or senior colleagues MUST BE sent via attached mail to =
paweena at ssi-tdr.net by August 5, 2005.  The reference letters MUST =
indicate why strong supports are given to the applicant and also need to =
describe how the institution and the applicant would benefit from =
attending this course.


Venue of the training course:

            Center for Bioinformatics and Applied Genomics (CBAG), =
Faculty of Science, Mahidol University, Rama VI Rd., Bangkok 10400, =



            There is no registration fee for the course.  Selected =
applicants will be provided training materials, economy round-trip =
airfare, accommodation and food during the entire period of the training =


No. of Participants: Limited to only 15 participants


Course language: English


Further Information:

Professor Worachart Sirawaraporn

Department of Biochemistry and Center for Bioinformatics and Applied =
Genomics (CBAG), Faculty of Science, Mahidol University

Rama VI Rd., Bangkok 10400

Tel.: 66-2-201-5605

Fax: 66-2-248-0375

Email: scwsr at mahidol.ac.th


Important Dates :

Announcement of Course: July 1, 2005

Application Deadline: August 5, 2005

Notification of Participants: August 12, 2005

Deadline for Acceptance by Participants: August 17, 2005

Course Dates: September 19-30, 2005


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