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Janine Sieja Hagerman jsh at ncgr.org
Mon Jun 29 19:59:29 EST 1998


SANTA FE, N.M., June 24 -- The National Center for Genome Resources
today announced the appointment of Michael M. Harpold, Ph.D., as Chief
Scientific Officer. Harpold joins the center from SIBIA
Neurosciences, Inc., where he served as Vice President, Research. He
will play a critical role in NCGR's efforts to enhance its
bioinformatics and computational biology initiatives.

We are all excited about bringing Michael on board, President
and CEO Donald J. McCarren, Ph.D., said. His broad and
significant experience in biological and medical research including
gene discovery and functional genomics, and his proven ability to
motivate interdisciplinary teams of scientists, will be instrumental
in shaping the future direction of NCGR.

As a founding member of the scientific staff of SIBIA (formerly known
as The Salk Institute Biotechnology/Industrial Associates, Inc.),
Harpold has directed the company's research efforts since its
inception in 1981. The La Jolla, California-based company has been a
leader in the development of a molecular target-based approach to drug
discovery utilizing genomics, together with novel functional bioassay
and high throughput screening technologies for the development of new
therapeutics to treat neurodegenerative, neuropsychiatric and
neurological disorders.

During Harpold's tenure, SIBIA's diverse array of research programs
included the development of a novel yeast (Pichia pastoris) recombinant
expression system and its use to produce potential human and animal
pharmaceutical and vaccine products, nucleic acid probe technologies for
diagnostics, gene transfer technologies applicable to human gene therapy
and agriculture, genetic modification of agricultural crops, and projects
involving industrial microbiology.

We're just at the beginning of a very exciting time in bioinformatic s
and genomics where the scope of biological investigation is expanding
from studying single genes or proteins to studying large groups of
genes and proteins, as well as their interactions in increasingly
sophisticated and systematic ways, Harpold said. NCGR is poised to
play a major role in bioinformatics and the new biology, and I'm eager
to guide that growth.

After earning his Ph.D. in developmental and molecular cell biology
from Tulane University and his B.Sci. in biology from Texas Christian
University, Harpold was a Helen Hay Whitney Postdoctoral Fellow in
molecular cell biology at Rockefeller University. He also was an NIH
Fell ow at the Marine Biological Laboratory at Woods Hole, Mass.

Harpold began his career as an assistant professor of biochemistry at
the University of Southern California School of Medicine, where he was
a memb er of the USC Cancer Center. He has published extensively on
his research in molecular biology and neuroscience and is an inventor
on more than 20 issued or pending patents.

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