[Bio-software] Polymorphism Information Content

lex via bio-soft%40net.bio.net (by obyupd from yahoo.com)
Thu Apr 1 18:39:13 EST 2010

Hi to all,


I'm looking for a program that calculates the Polymorphism Information Index (PIC) of a  molecular marker (e.g., SSR). Does anyone know where can I find that program? 

The program developed by Dr. Joel
Weller of Hebrew Univ. is no longer operational.     

Thank you in advance.

Orlex Yllano
PhD Student

<span style="font-weight:bold;font-style:italic;color:rgb(64, 127, 0);">"No eye has seen, no ear has heard, no mind has conceived what God has prepared for those who love Him" 1 Cor. 2:9</span>

----- Forwarded Message ----
From: "ppuigbo from gmail.com" <ppuigbo from gmail.com>
To: bio-soft from magpie.bio.indiana.edu
Sent: Thu, April 1, 2010 6:35:07 AM
Subject: [Bio-software] RCDI/eRCDI web-server for codon usage deoptimization

The RCDI server is a web-application that calculates the Relative Codon
Deoptimization Index (RCDI) and an expected value of the RCDI for a set of
query sequences by generating random sequences with similar G+C content and
amino acid composition to the input. The purpose of the server is to help in
the analysis of host-virus phylogenetic relationships or to infer the
potential host range of a virus and its replication strategy, as well as in
experimental virology to ease the step of gene design for heterologous
protein expression.

RCDI/E-RCDI is and update of the server CAIcal (
http://genomes.urv.cat/CAIcal). This server is freely accessible at

For more details see Puigbo et al. (2010) BMC Reasearch Notes, 3:87.
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