Dear Subscriber,
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UniProt Release 8.0 Note
30-May-2006
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CONTENTS
1. Introduction
2. Database description
3. Current release contents
4. Description of changes made to UniProt since release 7.0
5. Forthcoming changes
6. How to link to UniProt
7. Feedback
8. Acknowledgements
9. Terms of use
10. Citation
11. Contact
1. INTRODUCTION
The UniProt Consortium--European Bioinformatics Institute (EBI), Swiss
Institute of Bioinformatics (SIB) and Protein Information Resource
(PIR)--is pleased to announce UniProt Release 8.0 (30-May-2006). UniProt
is updated bi-weekly, and can be accessed online for searches or
download at http://www.uniprot.org.
2. DATABASE DESCRIPTION
UniProt is a centralized resource for protein sequences and functional
information. UniProt was created by joining together the information
from Swiss-Prot, TrEMBL and PIR. UniProt is comprised of three
components, each optimized for different uses: a) UniProt Knowledgebase
(UniProtKB), b) UniProt UniProt Reference Clusters (UniRef), and c)
UniProt Archive (UniParc). Additional information on UniProt is
available at http://www.uniprot.org/database/DBDescription.shtml and in
the UniProt Knowledgebase user manual
(http://expasy.org/sprot/userman.html).
3. CURRENT RELEASE CONTENTS
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UniProt Release 8.0
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Database -- Entries
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UniProtKB -- 3,170,612 (UniProtKB/Swiss-Prot section: 222,289;
UniProtKB/TrEMBL section: 2,948,323)
UniRef100 -- 3,511,676
UniRef90 -- 2,254,474
UniRef50 -- 1,148,123
UniParc -- 7,116,519
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Detailed release statistics for UniProtKB/Swiss-Prot and
UniProtKB/TrEMBL sections of the UniProt Knowledgebase can be viewed at
http://www.expasy.org/sprot/relnotes/relstat.html and
http://www.ebi.ac.uk/swissprot/sptr_stats/index.html, respectively.
4. DESCRIPTION OF CHANGES MADE TO UNIPROT SINCE RELEASE 7.0
UniProt Knowledgebase - To learn about the changes since the last major
release please read the UniProtKB/Swiss-Prot and UniProtKB/TrEMBL
release notes (http://expasy.org/sprot/relnotes/) and the recent changes
document (http://expasy.org/sprot/relnotes/sp_news.html).
5. FORTHCOMING CHANGES
Forthcoming changes concerning the UniProt Knowledgebase are described
in http://expasy.org/sprot/relnotes/sp_soon.html.
6. HOW TO LINK TO UNIPROT ENTRIES
How to link to UniProt entries can be found at
http://www.uniprot.org/support/docs/linkUniProt.html
7. FEEDBACK
We are constantly trying to improve our database in terms of accuracy
and representation and hence, consider your feedback extremely valuable.
Please contact us if you have any questions
(http://www.uniprot.org/support/helpdesk.shtml) or comments
(http://www.uniprot.org/support/feedback.shtml). You can also subscribe
to e-mail alerts (http://www.uniprot.org/support/alerts.shtml) for the
latest information on UniProt databases.
Submit new sequence data, updates and corrections at
http://www.uniprot.org/support/submissions.shtml
8. ACKNOWLEDGEMENTS
UniProt is mainly supported by the National Institutes of Health (NIH)
grant 1 U01 HG02712-01. Additional support for the EBI’s involvement in
UniProt comes from the two European Union contracts BioBabel
(QLRT-2000-00981) and TEMBLOR (QLRI-2001-00015) and from the NIH grant
1R01HGO2273-01. UniProtKB/Swiss-Prot activities at the SIB are supported
by the Swiss Federal Government through the Federal Office of Education
and Science. PIR activities are also supported by the NIH grants for
NIAID proteomic resource (HHSN266200400061C) and grid enablement
(NCI-caBIGICR-10-10-01) and National Science Foundation grants for
iProClass (DBI-0138188) and BioThesaurus (ITR-0205470).
9. TERMS OF USE
UniProt is available for both commercial and non-commercial use. Please
see http://www.uniprot.org/terms for details.
10. CITATION
If you want to cite UniProt in a publication please use the following
reference:
Wu CH, Apweiler R, Bairoch A, Natale DA, Barker WC, Boeckmann B, Ferro
S, Gasteiger E, Huang H, Lopez R, Magrane M, Martin MJ, Mazumder R,
O'Donovan C, Redaschi N, Suzek B. The Universal Protein Resource
(UniProt): an expanding universe of protein information. Nucleic Acids
Res. 2006 Jan 1;34(Database issue):D187-91.
11. CONTACT
EMBL Outstation
European Bioinformatics Institute (EBI)
Wellcome Trust Genome Campus
Hinxton
Cambridge CB10 1SD
United Kingdom
Telephone: (+44 1223) 494 444
Fax: (+44 1223) 494 468
Electronic mail address: datalib at ebi.ac.uk / swissprot at ebi.ac.uk
WWW server: http://www.ebi.ac.uk/
Swiss Institute of Bioinformatics (SIB)
Centre Medical Universitaire
1, rue Michel Servet
1211 Geneva 4
Switzerland
Telephone: (+41 22) 702 50 50
Fax: (+41 22) 702 58 58
Electronic mail address: swiss-prot at expasy.org
WWW server: http://www.expasy.org/
Protein Information Resource (PIR)
Georgetown University Medical Center
3300 Whitehaven Street NW
Suite 1200
Washington, DC 20007
United States of America
Telephone: (+1 202) 687 1039
Fax: (+1 202) 687 0057)
Electronic mail address: pirmail at georgetown.edu
WWW server: http://pir.georgetown.edu
Sincerely,
UniProt Help Desk
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