Dear Subscriber,
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UniProt Release 7.0 Note
07-Feb-2006
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CONTENTS
1. Introduction
2. Database description
3. Current release contents
4. Description of changes made to UniProt since release 6.0
5. Launch of UniProtKB Sequence/Annotation Version Database (UniSave)
6. Forthcoming changes
7. How to link to UniProt
8. Feedback
9. Acknowledgements
10. Terms of use
11. Citation
12. Contact
1. INTRODUCTION
The UniProt Consortium--European Bioinformatics Institute (EBI), Swiss
Institute of Bioinformatics (SIB) and Protein Information Resource
(PIR)--is pleased to announce UniProt Release 7.0 (07-Feb-2006). UniProt
is updated bi-weekly, and can be accessed online for searches or
download at http://www.uniprot.org.
2. DATABASE DESCRIPTION
UniProt is a centralized resource for protein sequences and functional
information. UniProt was created by joining together the information
from Swiss-Prot, TrEMBL and PIR. UniProt is comprised of three
components, each optimized for different uses: a) UniProt Knowledgebase
(UniProtKB), b) UniProt Non-redundant Reference databases (UniRef), and
c) UniProt Archive (UniParc). Additional information on UniProt is
available at http://www.uniprot.org/database/DBDescription.shtml and in
the UniProt Knowledgebase user manual
(http://expasy.org/sprot/userman.html).
3. CURRENT RELEASE CONTENTS
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UniProt Release 7.0
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Database -- Entries
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UniProtKB -- 2,812,716 (UniProtKB/Swiss-Prot section: 207,132;
UniProtKB/TrEMBL section: 2,605,584)
UniRef100 -- 3,085,801
UniRef90 -- 1,937,041
UniRef50 -- 994,914
UniParc -- 5,500,865
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Detailed release statistics for UniProtKB/TrEMBL and
UniProtKB/Swiss-Prot sections of the UniProt Knowledgebase can be viewed
at http://www.ebi.ac.uk/swissprot/sptr_stats/index.html and
http://www.expasy.org/sprot/relnotes/relstat.html, respectively.
4. DESCRIPTION OF CHANGES MADE TO UNIPROT SINCE RELEASE 6.0
UniProt Knowledgebase - To learn about the changes since the last major
release please read the UniProtKB/Swiss-Prot and UniProtKB/TrEMBL
release notes (http://expasy.org/sprot/relnotes/) and the recent changes
document (http://expasy.org/sprot/relnotes/sp_news.html).
5. LAUNCH OF UNIPROTKB SEQUENCE/ANNOTATION VERSION DATABASE (UniSave)
As part of UniProt release 7, the UniProt Consortium has launched the
UniProtKB Sequence/Annotation Version Database (UniSave), a
comprehensive archive of UniProtKB/Swiss-Prot and UniProtKB/TrEMBL entry
versions. Unlike the UniProt Knowledgebase which contains only the
latest Swiss-Prot and TrEMBL entry and sequence versions, the UniProtKB
Sequence/Annotation Version Database provides access to all versions of
these entries to allow tracking of sequence and annotation changes.
6. FORTHCOMING CHANGES
Forthcoming changes are described in
http://expasy.org/sprot/relnotes/sp_soon.html.
7. HOW TO LINK TO UNIPROT ENTRIES
A detailed description of how to link to UniProt entries can be found at
http://www.uniprot.org/support/docs/linkUniProt.html
8. FEEDBACK
We are constantly trying to improve our database in terms of accuracy
and representation and hence, consider your feedback extremely valuable.
Please contact us if you have any questions
(http://www.uniprot.org/support/helpdesk.shtml) or comments
(http://www.uniprot.org/support/feedback.shtml). You can also subscribe
to e-mail alerts (http://www.uniprot.org/support/alerts.shtml) for the
latest information on UniProt databases.
Submit new sequence data, updates and corrections at
http://www.uniprot.org/support/submissions.shtml
9. ACKNOWLEDGEMENTS
UniProt is supported mainly by the National Institutes of Health (NIH)
grant U01 HG02712. Minor support for the EBI's involvement in UniProt
comes from the European Union contracts BioBabel (QLRT-2000-00981) and
TEMBLOR (QLRI-2001-00015) and from the NIH grant R01 HGO2273. Swiss-Prot
activities at the SIB are supported by the Swiss Federal Government
through the Federal Office of Education and Science. PIR activities are
also supported by the National Science Foundation (NSF) grants
DBI-0138188 and ITR-0205470.
10. TERMS OF USE
UniProt is available for both commercial and non-commercial use. Please
see http://www.uniprot.org/terms for details.
11. CITATION
If you want to cite UniProt in a publication please use the following
reference:
Wu CH, Apweiler R, Bairoch A, Natale DA, Barker WC, Boeckmann B, Ferro
S, Gasteiger E, Huang H, Lopez R, Magrane M, Martin MJ, Mazumder R,
O'Donovan C, Redaschi N, Suzek B. The Universal Protein Resource
(UniProt): an expanding universe of protein information. Nucleic Acids
Res. 2006 Jan 1;34(Database issue):D187-91.
12. CONTACT
EMBL Outstation
European Bioinformatics Institute (EBI)
Wellcome Trust Genome Campus
Hinxton
Cambridge CB10 1SD
United Kingdom
Telephone: (+44 1223) 494 444
Fax: (+44 1223) 494 468
Electronic mail address: datalib at ebi.ac.uk / swissprot at ebi.ac.uk
WWW server: http://www.ebi.ac.uk/
Swiss Institute of Bioinformatics (SIB)
Centre Medical Universitaire
1, rue Michel Servet
1211 Geneva 4
Switzerland
Telephone: (+41 22) 702 50 50
Fax: (+41 22) 702 58 58
Electronic mail address: swiss-prot at expasy.org
WWW server: http://www.expasy.org/
Protein Information Resource (PIR)
Georgetown University Medical Center
3300 Whitehaven Street NW
Suite 1200
Washington, DC 20007
United States of America
Telephone: (+1 202) 687 2121
Fax: (+1 202) 687 0057
Electronic mail address: pirmail at georgetown.edu
WWW server: http://pir.georgetown.edu
Sincerely,
UniProt Help Desk
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