Announcing Pfam 14.0

[Mhairi Marshall]

                ANNOUNCING PFAM RELEASE 14.0
                ===========================


Pfam is a collection of protein domain family alignments which were
constructed semi-automatically using profile hidden Markov models. Pfam
families contain functional annotation and cross-references to other
databases.  Query sequences can be searched against the Pfam library of
profile hidden Markov models at the web sites below.

Pfam 14.0 contains 7459 families.  75% of proteins in SWISSPROT 43.2
and TrEMBL 26.2 have at least one match to a Pfam family.

For interactive access and searching see URLs

               http://www.sanger.ac.uk/Software/Pfam
               http://pfam.wustl.edu
               http://www.cgr.ki.se/Pfam

The release is also available in flat file by anonymous ftp:

               ftp://ftp.sanger.ac.uk/pub/databases/Pfam/
               ftp://ftp.genetics.wustl.edu/pub/Pfam/
               ftp://ftp.cgr.ki.se/pub/data/Pfam/

The Pfam HMM library is compatible with HMMER2 software, available from
               http://hmmer.wustl.edu/

and also the Wise2 software, available from

               http://www.sanger.ac.uk/Software/Wise2/

___________________
The Pfam consortium
09-06-2004




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Miss Mhairi Marshall                   Wellcome Trust Sanger Institute,
01223 494724                           Wellcome Trust Genome Campus,
http://www.sanger.ac.uk/Software/Pfam  Hinxton, Cambridge CB10 1SA, UK
http://www.sanger.ac.uk/Software/Rfam