IUBio

Removal of homologous sequences

Hans Stenien hans.stenoien at ebc.uu.se
Mon Jul 8 03:53:12 EST 2002



"Joseph Dale" <jdale at uclink.berkeley.edu> skrev i meddelandet
news:3D1CFC13.1040100 at uclink.berkeley.edu...

> (For sequence I/O libraries, see bioperl.org, biopython.org, etc.) The
> real question is: how do you detect homology? Is it enough to do a
> pairwise global or local alignment of two sequences and find a score or
> percent identity above some arbitrary threshold?

Yes. A blastn alignment e.g. with normalized score values compared to a
cut-off value is what I had in mind.

Hans





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