The program DynaFit, free for academic researchers,
was updated to version 3.25. This version features
an option to output the computed initial reaction
velocities at an arbitrary reaction time.
The program is most useful in the analysis of complex
reaction mechanism, for which traditional (algebraic)
kinetic equations cannot be derived. See bibliography
below for a list of 54 journal articles using DynaFit.
EXAMPLE: "TIGHT BINDING" INHIBITION OF AN ENZYME DIMER
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DYNAFIT INPUT
[mechanism]
Monomer + Monomer <==> Dimer : k1 k-1
Dimer + Inhibitor <==> Complex : k2 k-2
Dimer + Substrate <==> Intermediate : k3 k-3
Intermediate <==> Dimer + Product : k4 k-4
REFERENCES & LINKS
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Home page http://www.biokin.com/dynafit/
Donwload http://www.biokin.com/dynafit/download.html
User manual http://www.biokin.com/dynafit/scripting/
Bibliography http://www.biokin.com/dynafit/biblio.html
Reference P. Kuzmic (1996) Anal. Biochem. 237, 260-273.
Please contact me if you have any questions about
installing or running the program.
- P.K.
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P e t r K u z m i c, Ph. D. * BioKin Ltd.
1652 S. Grand Ave. * Suite 337 * Pullman, WA 99163
509.334.4131 * 509.332.3493 fax * http://www.biokin.com
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